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br Conflict of interest br Introduction
2024-07-18

Conflict of interest Introduction The Piezo proteins, Piezo1/FAM38A and Piezo2/FAM38B, are multi-pass transmembrane proteins that have been identified as mechanically-activated (MA) homomultimeric, pore-forming ion channels [1,2]. Piezo1 is broadly expressed with its highest expression in blad
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It is worth mentioning that cordycepin as an adenosine
2024-07-18

It is worth mentioning that cordycepin, as an adenosine analogue, is structurally similar to adenosine. A previous study has shown that the anti-apoptotic effects of cordycepin are partially dependent on the activation of A1R [16], and cordycepin increases theta waves power density via nonspecific a
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There is also a literature on the impact of commodity
2024-07-17

There is also a literature on the impact of commodity (consumption) taxation under imperfect competition. Besley (1989) applies a Cournot model, in which production takes place under IRS and in which free entry leads to an excessive number of firms in the market. Introducing a distortive specific co
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Similar to V the temporal neocortex of mammals including the
2024-07-17

Similar to V1, the temporal neocortex of mammals, including the primary auditory cortex (A1), is densely innervated by 5-HT fibers originating mainly in the dorsal raphe nucleus (Campbell et al., 1987, Harding and Paxinos, 2004, Törk, 1990), and the major melanin of 5-HTRs are expressed throughout t
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During the year study period of men in the
2024-07-17

During the 4-year study period, 19.9% of men in the dutasteride group developed prostate cancer as compared to 25.1% in the placebo group, which represents an absolute risk 71 4 synthesis of 5.1% for men taking dutasteride (Pe weighed against the prospect of undesirable sexual side effects and decre
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To help ensure the fidelity of mitosis and cytokinesis cells
2024-07-17

To help ensure the fidelity of mitosis and cytokinesis cells monitor these processes and delay cell cycle progression in response to certain defects. The spindle assembly checkpoint (SAC) is a surveillance system which delays Dexamethasone onset until a bipolar spindle has been correctly assembled
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Previous studies have demonstrated that the expression of
2024-07-17

Previous studies have demonstrated that the expression of the Aurora B gene is maximally increased at G2/M phage during mitosis (Honda et al., 2003, Fu et al., 2007, Goldenson and Crispino, 2015), and exhibits an extraordinary upregulation in a number of human cancers (Fu et al., 2007, Kollareddy et
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The ambiguity surrounding the role played by the LOXs
2024-07-17

The ambiguity surrounding the role played by the 15-LOXs in malignant biological processes stems also from the limitations of current animal models, and especially the usage of its 12/15-LOX murine homolog, which can also catalyze the production of 12-HETE. Indeed, the proinflammatory effect of 12-H
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We also show that in
2024-07-17

We also show that in both ATM proficient and deficient/mutant Cyprodime hydrochloride the activation of ATR signaling is DSB complexity-dependent (Figs. 1, 4A, C and E, 6A and B). Wang et al. have also reported that the effects of ATR and CHK1 on radiosensitivity are independent of the NHEJ repair p
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br Introduction The term antioxidant derives from the
2024-07-17

Introduction The term antioxidant derives from the prevention of the oxygen consumption. In the late of 19th centuries, antioxidants were generally used in industrial processes such as against to metal corrosion, vulcanization of rubber. Later on, the use of antioxidants to prevent the rancidity
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Recently whey products have been added to nutritional bevera
2024-07-17

Recently, whey products have been added to nutritional beverages to boost their antioxidant capacity. Supplementation of a lemon drink with 1% WP hydrolyzed by subtilisin increased the antioxidant activity of the beverage from 0.75 to 7.79 mmol of TE/L (Athira et al., 2014). In addition, a flavored
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br Acknowledgements This study was funded the Irish Departme
2024-07-17

Acknowledgements This study was funded the Irish Department of Agriculture, Food and the Marine through the research program FIRM/RSF/CoFoRD (Reference: 13 F 462). The authors declare no conflict of interest. Introduction Radiotherapy (RT) is one of the major treatment methods among patients
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br Conclusions br Introduction In
2024-07-17

Conclusions Introduction In the modern life of humans, Parthenolide are widely prescribed for therapy against bacterial diseases to prevent the onset of bacterial infections during a viral disease (Goossens et al., 2005; Van Boeckel et al., 2014). They have been massively administered and per
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mt t Insulin is the central hormone involved in the control
2024-07-17

Insulin is the central hormone involved in the control of glucose and lipid metabolism. Other nonmetabolic effects of insulin are intensively studied as well. Activation of insulin receptor not only promotes glucose uptake, protein synthesis, and inhibits lipid metabolism, but also is crucial for re
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Bioinformatics tools are becoming more powerful
2024-07-17

Bioinformatics tools are becoming more powerful and reliable due to the growing number and availability of experimentally determined protein structures (Arnold et al., 2006, Suplatov et al., 2015, Wiltgen and Tilz, 2009). The SWISS-MODEL and MODELLER programs are most frequently used for homology or
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