• Using the same methodology described above

  2018-10-22

  

  Using the same methodology described above, we analyzed 10 female hiPSC lines generated in 4 studies, in comparison to their parental somatic cells. Interestingly, the same three categories of XCI demonstrated for hESCs are also relevant for hiPSCs, emphasizing the resemblance of these two different

• Using the same methodology described above

  2018-10-22

  

  Using the same methodology described above, we analyzed 10 female hiPSC lines generated in 4 studies, in comparison to their parental somatic cells. Interestingly, the same three categories of XCI demonstrated for hESCs are also relevant for hiPSCs, emphasizing the resemblance of these two different

• As the stem cells were recovered from bears that recently

  2018-10-22

  

  As the stem PI103 were recovered from bears that recently were hibernating, it is possible that circulating factors that protect the bear from bone degeneration during hibernation prime the stem cells. That we did not see any chondrogenic differentiation in the cultures exposed to the chondrogenic

• br Results br Discussion Supplementation of the p

  2018-10-22

  

  Results Discussion Supplementation of the p38 MAPK inhibitor SB203580 has been identified to enhance cardiomyogenesis of human embryonic stem BTS cost at a relative narrow range of 1–10μM whereas higher concentrations >15μM inhibited or blocked cardiac differentiation (Graichen et al., 2008).

• Introduction The periosteum has recently been recognized

  2018-10-22

  

  Introduction The periosteum has recently been recognized as a promising source of immature progenitor cells that are not yet committed to specific cell lineages and osteogenic progenitors. For osteogenic cell processing in tissue engineering, the periosteum has generally been utilized to prepare di

• br Discussion We have described

  2018-10-22

  

  Discussion We have described an approach that achieves inducible, retrovirus-mediated gene expression by using the coding sequence of TFs fused to an ERT2 motif. Fusion of the ERT2 motif to two TFs that regulate fate-choice decisions in the course of adult neurogenesis (i.e., ASCL1 and NEUROD1) a

• According to these roles in the developing cerebellum we

  2018-10-22

  

  According to these roles in the developing cerebellum, we show that ASCL1 and NEUROG2 reprogram CerebAstro mostly into GABAergic iNs. Moreover, expression of calcium binding proteins reveals that ASCL1 and NEUROG2 lineage-reprogrammed CerebAstro iNs are distinct: while ASCL1 induces mostly CALBINDIN

• Our previous study Ara et al demonstrated

  2018-10-22

  

  Our previous study (Ara et al., 2011) demonstrated the protective efficacy of hypoxic-preconditioning against hypoxic–ischemic injury in newborn piglet model. We showed that hypoxic exposure for 3h, 24h before hypoxia–ischemia, was effective in reducing glucocorticoid receptors damage in newborn pi

• br Materials and methods br Results br Discussion In

  2018-10-22

  

  Materials and methods Results Discussion In this study we provide evidence that lung stromal erk inhibitor and their differentiated progeny have different capacities for the support of lung EpiSPC. We demonstrate that the expression of CD166 on primary isolated lung stromal cells correlates

• In this report we directly compared two cell types to

  2018-10-22

  

  In this report we directly compared two cell types to provide a hematopoietic stem/progenitor cell niche in a human system. Many authors have reported the ability of MSCs to expand the HSCs or CD34+ cells. However our flow cytometric studies demonstrated that the majority of the CD34+ Rapamycin Supp

• Interestingly despite culture condition for FGF ESCs and pre

  2018-10-20

  

  Interestingly, despite culture condition for FGF-ESCs and previously reported chimera-competent FGF-iPSCs (di Stefano et al., 2010) are quite similar, e.g., FGF2 and KSR with MEFs, their cytokine dependency seems different. Pluripotency of FGF-iPSCs, which is determined by the expression of exogenou

• xanthine oxidase inhibitor Peripheral blood mononuclear cell

  2018-10-20

  

  Peripheral blood mononuclear xanthine oxidase inhibitor (PBMCs) were obtained from a 43-year-old male with familial HCM. The patient fulfilled clinical criteria for HCM with a maximum left ventricular wall thickness of 28mm (normal 7–10mm) in the absence of loading conditions. The patient is hetero

• br Materials and methods br Results br Discussion Since the

  2018-10-20

  

  Materials and methods Results Discussion Since the report of iNSCs in 2012 (Sheng et al., 2012a,b), several other groups have also published studies on iNSCs, using different starter INNO-406 and reprogramming factors (Kim et al., 2014; Cheng et al., 2014a; Cheng et al., 2014b; Cheng, 2014

• br Materials and methods br Results

  2018-10-20

  

  Materials and methods Results Discussion This present study and previous works in the literature have shown that mechanical stimulation promotes the proliferation of BMSCs (Luu et al., 2009). In this study, the presented results revealed that pressure promoted BMSC proliferation by facilita

• dcb Supplier br Resource table Resource details Following th

  2018-10-20

  

  Resource table: Resource details Following their mechanical isolation from day 7 blastocysts, the inner cell masses (ICM) were seeded individually onto the feeder layers. After 2days of incubation, most of the ICMs were found attached to the feeder cells. The cultures were allowed to grow for 8–

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