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The above investigation indicates that discrete and
2018-11-02
The above investigation indicates that discrete and continuous models are common for layout representation. Most approaches adopt a 2-D layout representation. Approaches that directly modify three-dimensional (3-D) spaces are rare. This trend may be explained by conventional and technical reasons. F
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Diverticulosis has become a common
2018-11-02
Diverticulosis has become a common condition in developed countries, and its prevalence increases with age. Diverticulosis may occur anywhere in the gastrointestinal tract, with the sigmoid region accounting for > 85% of the cases. Diverticulitis, an infection of the diverticula, can lead to hemorrh
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Associated hyperostosis of the anterior skull base
2018-11-02
Associated hyperostosis of the anterior skull d-glucose is extremely rare for patients with ENBs. Meningioma-associated hyperostosis is relatively common, generally localized, and proportional to the tumor size; the potential pathogenesis of tumor-associated hyperostosis was considered to include h
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Introduction Buried penis is a congenital anomaly in which t
2018-11-02
Introduction Buried penis is a congenital anomaly in which the penis is normal in size but appears to be small (i.e., the external genitalia appear small). Parents of patients with this anomaly or patients themselves visit hospital because of the small appearance of the penis. In addition to the ab
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The climate is rapidly changing in the
2018-11-02
The climate is rapidly changing in the Arctic and will undoubtedly affect the interaction between parasites, the environment, and their hosts with potentially detrimental impacts on the health and welfare of Arctic peoples. These issues have been the subject of extensive scientific discussions in re
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LAB in fermented foods are of interest not only
2018-11-02
LAB in fermented foods are of interest not only for their role in fermentation but also for their role in promoting positive health impacts. The concept of beneficial health effects of LAB has existed since Metchnicoff in 1908 proposed that saha inhibitor manufacturer producing microorganisms in fe
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The effect of the relative HUVECs MSCs ratio was
2018-11-02
The effect of the relative HUVECs-MSCs ratio was also investigated. This aspect can be controversial since many different combinations were found in the literature: 4:1 (Santos et al., 2009), 2:1 (Guillotin et al., 2004; Villars et al., 2002; Grellier et al., 2009a; Guillotin et al., 2008; Grellier
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br Experimental Procedures Briefly hiPSCs were generated
2018-11-02
Experimental Procedures Briefly, hiPSCs were generated from IMR90, CCD-1097SK, BJ1, and NPC cells derived from 11-week-old fetal brain using retroviral expression of OCT4, SOX2, KLF4, and c-MYC or OCT4, NANOG, KLF4, and LIN-28. This study of hESCs and hiPSCs was approved by the UCLA Embryonic Ste
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pannexin-1 inhibitor NPCs NSCs are commonly isolated by manu
2018-11-02
NPCs/NSCs are commonly isolated by manually dissecting iPSC-derived neural rosettes formed in neural induction medium. Rosettes are dissociated into single pannexin-1 inhibitor or smaller clumps which are then cultured as floating neurospheres. Our results show that such an approach can enrich NSCs
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br Experimental Procedures br Acknowledgments
2018-11-02
Experimental Procedures Acknowledgments Introduction Master transcription regulators control the pluripotent gene expression in embryonic stem Outcome (ESCs) (Avilion et al., 2003; Chambers et al., 2003; Mitsui et al., 2003; Nichols et al., 1998). X chromosome inactivation (XCI) is a crucia
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The ISSCR has recently released updated guidelines on stem
2018-11-02
The ISSCR has recently released updated guidelines on stem cell research and clinical translation (Daley et al., 2016; ISSCR, 2016) that stress the importance of rigorous preclinical testing and recommends the publication of preclinical studies in full to allow assessment of the strength of the evid
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br Results br Discussion Although hiPSCs have been directed
2018-11-02
Results Discussion Although hiPSCs have been directed to differentiate into various organoids/tissues and in vitro differentiation from bovine iPSCs toward a partial mammary phenotype has been reported (Cravero et al., 2015), generation of mammary organoids/cells from hiPSCs has not been estab
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Introduction The research of hydrogen diffusion in solids is
2018-11-02
Introduction The research of hydrogen urat1 inhibitor in solids is of great practical value. The phenomena of hydrogen embrittlement and casting cracking during cooling and crystallization occur as a result of hydrogen diffusion. Gorsky proved in Refs. [1,2] that crystalline matrix deformations oc
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br Stress strain state of the
2018-11-02
Stress–strain state of the shell under axisymmetric loading Eqs. (6)–(8) can be reduced to an ODE system for a column of six unknown variables. This system has the form with the notations introduced ODE system (10) is supplemented by three boundary conditions for each edge of the shell. Thi
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Although there is no clear association between narcolepsy an
2018-11-02
Although there is no clear association between narcolepsy and PLMs, some studies demonstrated the important role of hypocretin-1 in this (-)-JQ1 association. Alteration of the autonomic regulation, sleep fragmentation and increase in the PLMs prevalence might be present in patients with narcolepsy
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