• br Methods br Results A total of cases including

  2019-06-14

  

  Methods Results A total of 2136 cases, including 614 controls, and 707 LAA, 375 SVO, and 440 HICH cases, were enrolled in this study. Clinical parameters between the control individuals and patients with different stroke subtypes are listed in Table 1. The average age and serum HDL-C level wer

• IL can induce phagocytosis cytoskeleton rearrangement gene e

  2019-06-14

  

  IL-15 can induce phagocytosis, cytoskeleton rearrangement, gene expression, de novo protein synthesis and can delay apoptosis in human neutrophils [15]. Production of chemokines, cytokines and natural inhibitors is increased in IL-15 induced neutrophils, including CXCL8 (IL-8) [16], IL-1beta, IL-1RI

• br Conclusion br Conflict of interest

  2019-06-14

  

  Conclusion Conflict of interest Introduction Loss-of-function mutations in the cardiac sodium (Na+) channel gene have been implicated in Brugada syndrome, progressive cardiac conduction defect (PCCD), sick sinus syndrome, and idiopathic ventricular fibrillation (IVF) [1]. In the present stu

• br Conflicts of interest br Acknowledgment This work was sup

  2019-06-14

  

  Conflicts of interest Acknowledgment This work was supported, in part, by a grant from the Experimental Research Center ELPEN (Y97/2-12-2013). The funding source had no involvement in the study design, in the collection, analysis and interpretation of data, in the writing of the report, and i

• HIV counselling and testing is the essential first step

  2019-06-14

  

  HIV counselling and testing is the essential first step to accessing HIV care services and is also recognised as an HIV prevention strategy because knowledge of HIV status reduces risky sexual behaviours. A reduction in the number of sexual partners has been reported, but not a significant increase

• This week the global health cynosure

  2019-06-14

  

  This week the global health cynosure has been the World Health Assembly (WHA) in Geneva. On the agenda we\'ve seen action plans galore: from tuberculosis control to disability to neonatal health. There have been follow-up reports on vaccination, non-communicable diseases, and nutrition. But one thin

• caspase pathway Although the study is of a high quality

  2019-06-13

  

  Although the study is of a high quality given the constraints of the case-control design, we question whether it alone provides sufficient evidence for this policy recommendation. Observational studies of ITNs are notoriously fraught with challenges. Even in settings in which randomised trials show

• br In the past year migration

  2019-06-13

  

  In the past year, migration to Europe from Africa and the Middle East has reached unprecedented levels. In 2016, 181 405 migrants reached the shores of Italy and more than 5000 died trying to reach the southern coasts of Europe. Many migrants seek to escape war, poverty, persecution, or ill treatm

• We have received funding from

  2019-06-13

  

  We have received funding from the Wellcome Trust to develop a global atlas of podoconiosis. We aim to advance new knowledge on the geographical distribution and spatial epidemiology of the disease. A first step in this work will be to establish the geographical absence of disease by applying an evi

• br Conclusions br Financial support br Conflict of interest

  2019-06-13

  

  Conclusions Financial support Conflict of interest Acknowledgment Introduction Cardiac resynchronization therapy (CRT) has been demonstrated to improve symptoms, quality of life, functional status, and reduce mortality and molarity conversion failure-related hospitalizations in patie

• br Genetic basis Similar to other arrhythmia syndromes Bruga

  2019-06-13

  

  Genetic basis Similar to other arrhythmia syndromes, Brugada and early repolarization syndromes are inherited diseases that are usually transmitted in an autosomal-dominant manner [26]. To date, 13 genes have been associated with Brugada syndrome. Loss-of-function mutations in SCN5A, encoding the

• The first variant in the non spine topic describes

  2019-06-13

  

  The first variant in the non-spine topic describes a patient with an excellent performance status, a favorable life expectancy, and an asymptomatic Senexin A lesion which does not pose an obvious risk for pathologic fracture. While the authors acknowledge that research has begun to determine whethe

• br Conclusion br Conflict of

  2019-06-13

  

  Conclusion Conflict of interest Case report He was transferred to our hospital due to cardiopulmonary arrest at age 45. An electrocardiogram revealed ventricular fibrillation, and sinus rhythm was restored by cardiac defibrillation. After intensive therapy, we planned an implantable cardiov

• br Autophagy and lipid metabolism LD formation is

  2019-06-13

  

  Autophagy and lipid metabolism LD formation is an indispensable step in lipid metabolism. The Atg8/LC3 conjugation system is essential for autophagosome membrane formation. However, some evidence suggests that Atg8/LC3 conjugation is also involved in LD formation. Indeed, LD formation is suppress

• br Imagine providing care for low birthweight LBW lighter

  2019-06-13

  

  Imagine providing care for 900 000 low birthweight (LBW; lighter than 2500 g) newborn babies each year in sub-Saharan Africa—all attributable to preventable and treatable malaria. Many of these LBW babies will be born in rural and impoverished settings where access to health care is poorest and th

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